HAIR REGROWTH
hair regeneration
WHAT IS STEM CELLS?
[What are hair stem cells? ]
We all have the ability to regenerate and replenish lost cells in our bodies, like skin and blood, in order to maintain tissues that are short-lived and constantly replaced. have cells Cells with these abilities are called “stem cells”. To be called a stem cell, the following two abilities are essential. One is the various cells that make up our bodies, such as skin, red blood cells, and platelets.
The ability to create (differentiation ability) and the ability to divide into cells with exactly the same ability as yourself (self-renewal ability).
Stem cells are divided into two types. One is stem cells, which continue to replace lost cells in certain tissues and organs, such as skin and blood. This type of stem cell is called a “tissue stem cell”. Tissue stem cells do not become anything, but their role is determined, for example, hematopoietic stem cells that create blood are cells of the blood system, and neural stem cells that create the nervous system are only cells of the nervous system. The other is "Pluripotent Stem Cells", like ES cells (Embryonic Stem Cells), which can produce any kind of cells in our body. In other words, pluripotent stem cells can also produce various tissue stem cells in our bodies.
iPS cells (induced pluripotent stem cells) are "pluripotent stem cells" artificially created from normal cells.
Research on a new treatment method called "regenerative medicine" that uses the properties of "stem cells" to treat injuries and illnesses using the cells themselves as medicine,
Research is progressing to examine the mechanism of disease by reproducing the state of cells in the body outside the body.
ABOUT PREVENTION OF HAIR LOSS
About prevention of hair loss
Autologous adipose-derived mesenchymal stem cell therapy to prevent progression of hair loss
What is alopecia
The total number of human hairs is said to be 100,000 to 150,000, but hair naturally stops growing when it grows to a certain extent. 2-5 years for males, 4-7 years for females. Cell division stops around the hair bulb and hair growth stops. Then, after a regression period of about 3 weeks, it enters a dormant period and eventually falls out. In this way, all hair is destined to fall out eventually, but after 4 to 6 months, the anagen hair (early anagen hair in the downy hair stage) will regenerate and he will come back. Normally, hair repeats this cycle, but due to some factors such as excessive secretion of male hormones, stress, and poor blood flow in the scalp, the period of the growth period becomes shorter than usual. The hair is falling out, and the hair loss is progressing.
Method of treatment
In the bulge region at the base of the hair follicle, there are “hair follicle stem cells” that produce hair, and hair is generated through cell division. When the function of these hair follicle stem cells deteriorates, the cycle from the resting phase to the growing phase stops, causing abnormalities in the hair cycle. At our clinic, by injecting adipose-derived stem cells directly into the scalp and activating hair follicle stem cells, we return the hair cycle to normal and promote hair growth. By injecting stem cells, the "progenitor cells" that exist around the hair root are activated. Growth factors produced by these cells act on dormant hair follicle stem cells, activating them to switch the transition from the resting phase to the anagen phase, promoting hair growth.
FLOW
Treatment flow
Our hospital is equipped with an environment that allows us to provide medical care to overseas patients.
In addition to Japanese, we are able to communicate with patients in Chinese, Vietnamese, English, French, and Mongolian.
The interpreters are staff members of the hospital who are capable of smooth communication with the attending physician even if they are of different nationalities.
1. inquiry
Please contact us by providing a photo of your hair and a photo of your face along with your personal identification (ID card, passport, etc.).
2, counseling
After you fill out the questionnaire that we will give you, the doctor will explain the stem cell treatment. Materials you have been waiting for
Based on this, we will propose a treatment that is suitable for your current health condition.
3, cell collection and blood collection
1. It takes about 20 minutes and uses local anesthesia.
2. After collecting cells with a diameter of about 5 mm from the skin behind the ear, blood will also be collected.
3. Sew using safe medical dissolvable thread.
4. After collecting the cells, the nurse will check the wound and administer medicine.
I'll give it to you.
4、Payment
Our clinic is a free medical treatment.
Counseling is free of charge, but payment will be made at the time of cell collection.
Payment can be made by credit card (JCB not accepted), UnionPay, wechat pay, Alipay, Line Pay, and overseas transfer.
5. Cell culture
We will start culturing stem cells and exosomes in our own lab.
The culture period is about 4 weeks.
We will start culturing cells in the best condition 4 weeks prior to your administration date, so we cannot change or cancel the administration date.
Reservation for the day of administration will be accepted after the payment of fees for cell collection, etc. has been completed.
Regenerative medicine clinic with in-hospital CPC
Currently, many regenerative medicine clinics obtain cultured cells by “outsourcing cell culture work” or “purchasing from outside”. However, at our hospital, we have set up an in-hospital CPC, and the collection, storage, culture, and testing are all performed in the same laboratory, and everything is centrally managed using barcodes. We also have GMP lab and ISO9001 certification.
Proprietary medium recipe
Medium is the most important factor in quality cell culture. At our hospital, we use “Helene Medium,” a proprietary medium for mesenchymal stem cells developed in our laboratory. Experimental results show that the growth curve and growth rate of the same medium are stable and several thousand times faster than commercial media, regardless of the presence or absence of serum [1] ISCT (the International Society for Cellular Therapy, [2] It is open to the public at overseas conferences such as the Cambridge International Stem Cell Symposium.
[1] “Cartilage regeneration by autologous adipose-derived mesenchymal stem cells for the treatment of osteoarthritis” was posted in ISCT (the International Society for Cellular Therapy) from May 29 to June 1, 2019
(http://www.isct2019.com/)
[2] “The Helene Medium: Specialized Stem Cell Culture Medium” was in Cambridge International Stem Cell Symposium from Sep. 19 to Sep.21, 2018.
Third-party cell quality certification
We outsource tests similar to those performed by Takara Bio Co., Ltd., and provide cells to patients after conducting the same tests in our laboratory. As a result of verifying the quality of stem cells impartially provided to patients by a third-party inspection company, what we provide is proven to be genuine mesenchymal stem cells. Our cells are not infected by the culture process and do not become cancerous. It also has the differentiation ability unique to stem cells. These test certificates are also attached to the patient who is actually administered.
6. Cell administration
Inject hair stem cells into areas of concern while consulting with a doctor.
*In the case of a syringe: insert the injection needle (24G)
*In the case of U225 (the latest high-quality injector developed to give intradermal injections made in France)
・There is little pain even without anesthesia due to stability during injection and less vibration.
・A maximum of 425 shots can be injected per minute
Treatment risks and side effects
* Hearing loss, dizziness, tinnitus, renal disorder, hypoglycemia, infection, other (anaphylactic reaction <cold sweat, nausea, vomiting, abdominal pain, dyspnea, decreased blood pressure>, pain at the puncture site, internal bleeding, neuropathy)
7. End of treatment
Before you go home, the staff will tell you what to do after treatment. You can go home (return home) from the same day. Considering the effects of medicines and postoperative pain, please refrain from coming to the hospital by car or motorcycle to prevent danger.
If you have any concerns after returning home, please feel free to contact us. Our staff and doctors will get back to you as soon as possible.
If you would like to consult with us before coming to the hospital, please contact us from "email consultation".
HAIR REGROWTH
hair regeneration
WHAT IS STEM CELLS?
[ What are hair stem cells? ]
We all have the ability to regenerate and replenish lost cells in our bodies, like skin and blood, in order to maintain tissues that are short-lived and constantly replaced. have cells Cells with these abilities are called “stem cells”. To be called a stem cell, the following two abilities are essential. One is the various cells that make up our bodies, such as skin, red blood cells, and platelets.
The ability to create (differentiation ability) and the ability to divide into cells with exactly the same ability as yourself (self-renewal ability).
Stem cells are divided into two types. One is stem cells, which continue to replace lost cells in certain tissues and organs, such as skin and blood. This type of stem cell is called a “tissue stem cell”. Tissue stem cells do not become anything, but their role is determined, for example, hematopoietic stem cells that create blood are cells of the blood system, and neural stem cells that create the nervous system are only cells of the nervous system. The other is "Pluripotent Stem Cells", like ES cells (Embryonic Stem Cells), which can produce any kind of cells in our body. In other words, pluripotent stem cells can also produce various tissue stem cells in our bodies.
iPS cells (induced pluripotent stem cells) are "pluripotent stem cells" artificially created from normal cells.
Research on a new treatment method called "regenerative medicine" that uses the properties of "stem cells" to treat injuries and illnesses using the cells themselves as medicine,
Research is progressing to examine the mechanism of disease by reproducing the state of cells in the body outside the body.
ABOUT PREVENTION OF ARTERIO SCLEROSIS
About prevention of hair loss
Aimed at preventing hair loss
Autologous adipose-derived mesenchymal stem cell therapy
What is alopecia
The total number of human hairs is said to be 100,000 to 150,000, but hair naturally stops growing when it grows to a certain extent. 2-5 years for males, 4-7 years for females. Cell division stops around the hair bulb and hair growth stops. Then, after a regression period of about 3 weeks, it enters a dormant period and eventually falls out. In this way, all hair is destined to fall out eventually, but after 4 to 6 months, the anagen hair (early anagen hair in the downy hair stage) will regenerate and he will come back. Normally, hair repeats this cycle, but due to some factors such as excessive secretion of male hormones, stress, and poor blood flow in the scalp, the period of the growth period becomes shorter than usual. The hair is falling out, and the hair loss is progressing.
Method of treatment
In the bulge region at the base of the hair follicle, there are “hair follicle stem cells” that produce hair, and hair is generated through cell division. When the function of these hair follicle stem cells deteriorates, the cycle from the resting phase to the growing phase stops, causing abnormalities in the hair cycle. At our clinic, by injecting adipose-derived stem cells directly into the scalp and activating hair follicle stem cells, we return the hair cycle to normal and promote hair growth. By injecting stem cells, the "progenitor cells" that exist around the hair root are activated. Growth factors produced by these cells act on dormant hair follicle stem cells, activating them to switch the transition from the resting phase to the anagen phase, promoting hair growth.
FLOW
Treatment flow
Our hospital is equipped with an environment that allows us to provide medical care to overseas patients.
In addition to Japanese, we are able to communicate with patients in Chinese, Vietnamese, English, French, and Mongolian.
The interpreters are staff members of the hospital who are capable of smooth communication with the attending physician even if they are of different nationalities.
1. inquiry
Please contact us by providing a photo of your hair and a photo of your face along with your personal identification (ID card, passport, etc.).
2, counseling
After you fill out the questionnaire that we will give you, the doctor will explain the stem cell treatment. Materials you have been waiting for
Based on this, we will propose a treatment that is suitable for your current health condition.
3, cell collection and blood collection
1. It takes about 20 minutes and uses local anesthesia.
2. After collecting cells with a diameter of about 5 mm from the skin behind the ear, blood will also be collected.
3. Sew using safe medical dissolvable thread.
4. After collecting the cells, the nurse will check the wound and administer medicine.
I'll give it to you.
4、Payment
Our clinic is a free medical treatment.
Counseling is free of charge, but payment will be made at the time of cell collection.
Credit card (JCB not accepted), UnionPay, wechat pay,
Payment can be made by Alipay, Line Pay, and overseas transfer.
5. Cell culture
We will start culturing stem cells and exosomes in our own lab.
The culture period is about 4 weeks.
We will start culturing cells in the best condition 4 weeks prior to your administration date, so we cannot change or cancel the administration date.
Reservation for the day of administration will be accepted after the payment of fees for cell collection, etc. has been completed.
Regenerative medicine clinic with in-hospital CPC
Currently, many regenerative medicine clinics obtain cultured cells by “outsourcing cell culture work” or “purchasing from outside”. However, at our hospital, we have set up an in-hospital CPC, and the collection, storage, culture, and testing are all performed in the same laboratory, and everything is centrally managed using barcodes. We also have GMP lab and ISO9001 certification.
Proprietary medium recipe
Medium is the most important factor in quality cell culture. At our hospital, we use “Helene Medium,” a proprietary medium for mesenchymal stem cells developed in our laboratory. Experimental results show that the growth curve and growth rate of the same medium are stable and several thousand times faster than commercial media, regardless of the presence or absence of serum [1] ISCT (the International Society for Cellular Therapy, [2] It is open to the public at overseas conferences such as the Cambridge International Stem Cell Symposium.
[1] “Cartilage regeneration by autologous adipose-derived mesenchymal stem cells for the treatment of osteoarthritis” was posted in ISCT (the International Society for Cellular Therapy) from May 29 to June 1, 2019
(http://www.isct2019.com/)
[2] “The Helene Medium: Specialized Stem Cell Culture Medium” was in Cambridge International Stem Cell Symposium from Sep. 19 to Sep.21, 2018.
Third-party cell quality certification
We outsource tests similar to those performed by Takara Bio Co., Ltd., and provide cells to patients after conducting the same tests in our laboratory. As a result of verifying the quality of stem cells impartially provided to patients by a third-party inspection company, what we provide is proven to be genuine mesenchymal stem cells. Our cells are not infected by the culture process and do not become cancerous. It also has the differentiation ability unique to stem cells. These test certificates are also attached to the patient who is actually administered.
（１）Stem cell quality experiment report
6. Dosing
While consulting with your doctor
Inject hair stem cells into the area of concern.
Treatment time: 20-30 minutes
injection into the scalp
Inject hair stem cells into areas of concern while consulting with a doctor.
*In the case of a syringe: insert the injection needle (24G)
* U225 device (the latest high-quality injector developed to give intradermal injections made in France)
・There is little pain even without anesthesia due to stability during injection and less vibration.
・A maximum of 425 shots can be injected per minute
7. End of treatment
Before you go home, the staff will tell you what to do after treatment. You can go home (return home) from the same day. Considering the effects of medicines and postoperative pain, please refrain from coming to the hospital by car or motorcycle to prevent danger.
If you have any concerns after returning home, please feel free to contact us. Our staff and doctors will get back to you as soon as possible.
