{"id":849,"date":"2026-05-06T17:09:09","date_gmt":"2026-05-06T08:09:09","guid":{"rendered":"https:\/\/stemcells.jp\/topics\/?p=849"},"modified":"2026-05-06T17:09:09","modified_gmt":"2026-05-06T08:09:09","slug":"chronic-fatigue-blood-sugar-energy-metabolism","status":"publish","type":"post","link":"https:\/\/stemcells.jp\/topics\/chronic-fatigue-blood-sugar-energy-metabolism\/","title":{"rendered":"\u6162\u6027\u7684\u306a\u75b2\u52b4\u306f\u8840\u7cd6\u5024\u306e\u4e71\u308c\u304c\u539f\u56e0\uff1f\u4f53\u306e\u30a8\u30cd\u30eb\u30ae\u30fc\u4ee3\u8b1d\u3068\u306e\u95a2\u4fc2"},"content":{"rendered":"<p>\u300c\u305f\u3063\u3077\u308a\u5bdd\u305f\u306f\u305a\u306a\u306e\u306b\u75b2\u308c\u304c\u53d6\u308c\u306a\u3044\u300d\u300c\u9031\u672b\u3082\u4f53\u304c\u91cd\u304f\u3066\u52d5\u3051\u306a\u3044\u300d\u2026\u202640\u301c60\u4ee3\u306e\u50cd\u304d\u76db\u308a\u3092\u60a9\u307e\u305b\u308b\u6162\u6027\u75b2\u52b4\u306e\u6b63\u4f53\u306f\u3001\u5e74\u9f62\u306e\u305b\u3044\u3060\u3051\u3067\u306f\u306a\u3044\u304b\u3082\u3057\u308c\u307e\u305b\u3093\u3002\u3053\u306e\u3088\u3046\u306a\u6162\u6027\u7684\u306a\u75b2\u308c\u306b\u306f\u3001\u8840\u7cd6\u5024\u306e\u4e71\u308c\u306b\u3088\u308b\u30a8\u30cd\u30eb\u30ae\u30fc\u4e0d\u8db3\u304c\u95a2\u4e0e\u3057\u3066\u3044\u308b\u53ef\u80fd\u6027\u304c\u3042\u308a\u307e\u3059\u3002<\/p>\n<p>\u3053\u306e\u8a18\u4e8b\u3067\u306f\u3001\u306a\u305c\u9ad8\u8840\u7cd6\u304c\u91cd\u3044\u75b2\u52b4\u611f\u3092\u62db\u304f\u306e\u304b\u3001\u30df\u30c8\u30b3\u30f3\u30c9\u30ea\u30a2\u306e\u50cd\u304d\u304b\u3089\u8a73\u3057\u304f\u89e3\u8aac\u3057\u307e\u3059\u3002<\/p>\n<div 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href=\"https:\/\/kennet.mhlw.go.jp\/information\/information\/heart\/k-02-008\">\u539a\u751f\u52b4\u50cd\u7701\uff5c\u5065\u5eb7\u65e5\u672c21\u30a2\u30af\u30b7\u30e7\u30f3\u652f\u63f4\u30b7\u30b9\u30c6\u30e0\u3000\uff5e\u5065\u5eb7\u3065\u304f\u308a\u30b5\u30dd\u30fc\u30c8\u30cd\u30c3\u30c8\uff5e\u300c\u7761\u7720\u3068\u751f\u6d3b\u7fd2\u6163\u75c5\u3068\u306e\u6df1\u3044\u95a2\u4fc2\u300d<\/a><\/p>\n<h3><span class=\"ez-toc-section\" id=\"%E8%84%B3%E3%81%A8%E7%AD%8B%E8%82%89%E3%81%8C%E7%96%B2%E5%8A%B4%E3%82%92%E8%B5%B7%E3%81%93%E3%81%99%E3%83%A1%E3%82%AB%E3%83%8B%E3%82%BA%E3%83%A0\"><\/span>\u8133\u3068\u7b4b\u8089\u304c\u75b2\u52b4\u3092\u8d77\u3053\u3059\u30e1\u30ab\u30cb\u30ba\u30e0<span 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class=\"ez-toc-section\" id=\"%E3%83%9F%E3%83%88%E3%82%B3%E3%83%B3%E3%83%89%E3%83%AA%E3%82%A2%E3%81%AE%E6%A9%9F%E8%83%BD%E4%BD%8E%E4%B8%8B%E3%81%A8%E9%AB%98%E8%A1%80%E7%B3%96%E3%81%AE%E6%82%AA%E5%BE%AA%E7%92%B0\"><\/span>\u30df\u30c8\u30b3\u30f3\u30c9\u30ea\u30a2\u306e\u6a5f\u80fd\u4f4e\u4e0b\u3068\u9ad8\u8840\u7cd6\u306e\u60aa\u5faa\u74b0<span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p>\u75b2\u52b4\u611f\u306e\u539f\u56e0\u3092\u63a2\u308b\u3046\u3048\u3067\u6b20\u304b\u305b\u306a\u3044\u306e\u304c\u3001\u7d30\u80de\u5185\u306b\u3042\u308b\u30df\u30c8\u30b3\u30f3\u30c9\u30ea\u30a2\u306e\u5b58\u5728\u3067\u3059\u3002\u9ad8\u8840\u7cd6\u304c\u3053\u306e\u5668\u5b98\u306b\u3069\u306e\u3088\u3046\u306a\u30c0\u30e1\u30fc\u30b8\u3092\u4e0e\u3048\u308b\u306e\u304b\u89e3\u8aac\u3057\u307e\u3059\u3002<\/p>\n<h3><span class=\"ez-toc-section\" id=\"%E7%B4%B0%E8%83%9E%E5%86%85%E3%81%AE%E3%83%9F%E3%83%88%E3%82%B3%E3%83%B3%E3%83%89%E3%83%AA%E3%82%A2%E3%81%AE%E5%BD%B9%E5%89%B2\"><\/span>\u7d30\u80de\u5185\u306e\u30df\u30c8\u30b3\u30f3\u30c9\u30ea\u30a2\u306e\u5f79\u5272<span class=\"ez-toc-section-end\"><\/span><\/h3>\n<p>\u79c1\u305f\u3061\u306e\u7d30\u80de\u306e\u4e2d\u306b\u306f\u3001\u53d6\u308a\u8fbc\u3093\u3060\u7cd6\u3084\u8102\u80aa\u3092\u71c3\u3084\u3057\u3001ATP\uff08\u30a2\u30c7\u30ce\u30b7\u30f3\u4e09\u30ea\u30f3\u9178\uff09\u3068\u3044\u3046\u751f\u547d\u6d3b\u52d5\u306e\u30a8\u30cd\u30eb\u30ae\u30fc\u3092\u4f5c\u308a\u51fa\u3059\u30df\u30c8\u30b3\u30f3\u30c9\u30ea\u30a2\u304c\u5b58\u5728\u3057\u3066\u3044\u307e\u3059\u3002\u3057\u304b\u3057\u3001\u30df\u30c8\u30b3\u30f3\u30c9\u30ea\u30a2\u306b\u306f\u52a0\u9f62\u306b\u3088\u3063\u3066\u6a5f\u80fd\u969c\u5bb3\u3092\u751f\u3058\u3084\u3059\u3044\u7279\u5fb4\u304c\u3042\u308a\u307e\u3059\u3002\u82e5\u3044\u9803\u306f\u98df\u3079\u305f\u3082\u306e\u3092\u52b9\u7387\u3088\u304f\u30a8\u30cd\u30eb\u30ae\u30fc\u306b\u5909\u63db\u3067\u304d\u3066\u3082\u3001\u52a0\u9f62\u3068\u3068\u3082\u306b\u305d\u3046\u306f\u3044\u304b\u306a\u304f\u306a\u3063\u3066\u3057\u307e\u3046\u306e\u3067\u3059\u3002<\/p>\n<p>\u51fa\u5178\uff1a<a href=\"https:\/\/www.jstage.jst.go.jp\/article\/tonyobyo\/51\/4\/51_4_295\/_pdf\">\u7cd6\u5c3f\u75c5 51(4)\uff1a295\u223c297, 2008\uff5c\u30df\u30c8\u30b3\u30f3\u30c9\u30ea\u30a2\u306b\u304a\u3051\u308b\u52a0\u9f62\u5909\u5316\u3068\u7cd6\u4ee3\u8b1d<\/a><\/p>\n<h3><span class=\"ez-toc-section\" id=\"%E9%85%B8%E5%8C%96%E3%82%B9%E3%83%88%E3%83%AC%E3%82%B9%E3%81%AB%E3%82%88%E3%82%8B%E3%83%9F%E3%83%88%E3%82%B3%E3%83%B3%E3%83%89%E3%83%AA%E3%82%A2%E6%A9%9F%E8%83%BD%E9%9A%9C%E5%AE%B3\"><\/span>\u9178\u5316\u30b9\u30c8\u30ec\u30b9\u306b\u3088\u308b\u30df\u30c8\u30b3\u30f3\u30c9\u30ea\u30a2\u6a5f\u80fd\u969c\u5bb3<span class=\"ez-toc-section-end\"><\/span><\/h3>\n<p>\u8840\u7cd6\u5024\u304c\u9ad8\u3044\u72b6\u614b\u304c\u7d9a\u304f\u3068\u3001\u7d30\u80de\u5185\u3067\u6d3b\u6027\u9178\u7d20\u304c\u767a\u751f\u3057\u3001\u5f37\u3044\u9178\u5316\u30b9\u30c8\u30ec\u30b9\u3092\u751f\u307f\u51fa\u3057\u307e\u3059\u3002\u3053\u306e\u9178\u5316\u30b9\u30c8\u30ec\u30b9\u306f\u30df\u30c8\u30b3\u30f3\u30c9\u30ea\u30a2\u306e\u6a5f\u80fd\u3092\u4f4e\u4e0b\u3055\u305b\u3001\u3055\u3089\u306b\u306f\u5f62\u614b\u7570\u5e38\u307e\u3067\u5f15\u304d\u8d77\u3053\u3059\u306e\u3067\u3059\u3002\u305d\u306e\u7d50\u679c\u3001ATP\u304c\u4f5c\u308c\u306a\u304f\u306a\u308a\u3001\u3055\u3089\u306b\u75b2\u308c\u3084\u3059\u3044\u4f53\u306b\u306a\u308b\u3068\u3044\u3046\u60aa\u5faa\u74b0\u306b\u9665\u308a\u307e\u3059\u3002\u3053\u3046\u3057\u305f\u30df\u30c8\u30b3\u30f3\u30c9\u30ea\u30a2\u306e\u6a5f\u80fd\u7570\u5e38\u304c\u30012\u578b\u7cd6\u5c3f\u75c5\u306e\u767a\u75c7\u306b\u95a2\u4e0e\u3059\u308b\u53ef\u80fd\u6027\u304c\u3042\u308b\u3068\u3082\u8003\u3048\u3089\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n<p>\u51fa\u5178\uff1a<a href=\"https:\/\/twinkle.repo.nii.ac.jp\/record\/21999\/files\/81e2000005.pdf\">\u6771\u4eac\u5973\u5b50\u533b\u79d1\u5927\u5b66\u5b66\u8853\u30ea\u30dd\u30b8\u30c8\u30ea\uff5c\u7cd6\u5c3f\u75c5\u3068\u30df\u30c8\u30b3\u30f3\u30c9\u30ea\u30a2\u6a5f\u80fd<\/a><\/p>\n<h2><span class=\"ez-toc-section\" id=\"%E3%81%A8%E3%82%8C%E3%81%AA%E3%81%84%E7%96%B2%E5%8A%B4%E3%82%92%E3%82%B1%E3%82%A2%E3%81%99%E3%82%8B%E6%96%B9%E6%B3%95%E3%81%A8%E5%86%8D%E7%94%9F%E5%8C%BB%E7%99%82\"><\/span>\u3068\u308c\u306a\u3044\u75b2\u52b4\u3092\u30b1\u30a2\u3059\u308b\u65b9\u6cd5\u3068\u518d\u751f\u533b\u7642<span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p>\u30df\u30c8\u30b3\u30f3\u30c9\u30ea\u30a2\u3092\u5065\u5eb7\u306b\u4fdd\u3061\u3001\u91cd\u3044\u75b2\u52b4\u3092\u89e3\u6d88\u3059\u308b\u305f\u3081\u306b\u306f\u3001\u3069\u306e\u3088\u3046\u306a\u5bfe\u7b56\u304c\u5fc5\u8981\u306a\u306e\u3067\u3057\u3087\u3046\u304b\u3002\u65e5\u5e38\u306e\u30b1\u30a2\u3068\u6700\u65b0\u533b\u7642\u306e\u4e21\u9762\u304b\u3089\u3054\u7d39\u4ecb\u3057\u307e\u3059\u3002<\/p>\n<h3><span class=\"ez-toc-section\" id=\"%E6%97%A5%E5%B8%B8%E3%81%A7%E3%81%A7%E3%81%8D%E3%82%8B%E3%83%9F%E3%83%88%E3%82%B3%E3%83%B3%E3%83%89%E3%83%AA%E3%82%A2%E6%B4%BB%E6%80%A7%E5%8C%96%E3%82%B1%E3%82%A2\"><\/span>\u65e5\u5e38\u3067\u3067\u304d\u308b\u30df\u30c8\u30b3\u30f3\u30c9\u30ea\u30a2\u6d3b\u6027\u5316\u30b1\u30a2<span class=\"ez-toc-section-end\"><\/span><\/h3>\n<p>\u30df\u30c8\u30b3\u30f3\u30c9\u30ea\u30a2\u3092\u5143\u6c17\u306b\u4fdd\u3064\u306b\u306f\u3001\u65e5\u3005\u306e\u8840\u7cd6\u5024\u30b3\u30f3\u30c8\u30ed\u30fc\u30eb\u304c\u5927\u5207\u3067\u3059\u30022\u578b\u7cd6\u5c3f\u75c5\u306e\u5834\u5408\u3001\u30a8\u30cd\u30eb\u30ae\u30fc\u5236\u9650\u3084\u77ed\u671f\u7684\u306a\u70ad\u6c34\u5316\u7269\u5236\u9650\u3001\u4f4eGI\u98df\u3001\u7a4d\u6975\u7684\u306a\u98df\u7269\u7e4a\u7dad\u306e\u6442\u53d6\u304c\u6709\u52b9\u3068\u3055\u308c\u3066\u3044\u307e\u3059\u3002\u307e\u305f\u3001\u6297\u9178\u5316\u4f5c\u7528\u306b\u512a\u308c\u305f\u30d3\u30bf\u30df\u30f3C\u3084\u304a\u8336\u306e\u30dd\u30ea\u30d5\u30a7\u30ce\u30fc\u30eb\u985e\u3092\u6442\u308b\u3053\u3068\u3082\u826f\u3044\u3067\u3057\u3087\u3046\u3002\u9069\u5ea6\u306a\u30a6\u30a9\u30fc\u30ad\u30f3\u30b0\u306a\u3069\u306e\u6709\u9178\u7d20\u904b\u52d5\u306f\u3001\u6297\u9178\u5316\u9175\u7d20\u3092\u8a98\u5c0e\u3057\u30a4\u30f3\u30b9\u30ea\u30f3\u611f\u53d7\u6027\u3092\u9ad8\u3081\u308b\u5065\u5eb7\u5897\u9032\u52b9\u679c\u304c\u671f\u5f85\u3067\u304d\u307e\u3059\u3002<\/p>\n<p>\u51fa\u5178\uff1a<a href=\"https:\/\/www.jds.or.jp\/uploads\/files\/publications\/gl2024\/03_1.pdf\">\u7cd6\u5c3f\u75c5\u8a3a\u7642\u30ac\u30a4\u30c9\u30e9\u30a4\u30f32024\uff5c3\u7ae0\u3000\u98df\u4e8b\u7642\u6cd5<\/a><br \/>\n<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/33096250\/\">Defective biosynthesis of ascorbic acid in Sod1-deficient mice results in lethal damage to lung tissue<\/a><br \/>\n<a href=\"https:\/\/niconurs.repo.nii.ac.jp\/record\/541\/files\/70009-015.pdf\">\u65b0\u6f5f\u770c\u7acb\u770b\u8b77\u5927\uff5c\u6d3b\u6027\u9178\u7d20\u3092\u6d88\u53bb\u3059\u308b\u6297\u9178\u5316\u7269\u8cea\u3067\u3042\u308b\u304a\u8336\u985e\u306e\u6297\u9178\u5316\u80fd\u6bd4\u8f03<\/a><br \/>\n<a href=\"https:\/\/www.jds.or.jp\/uploads\/files\/publications\/gl2024\/04_1.pdf\">\u7cd6\u5c3f\u75c5\u8a3a\u7642\u30ac\u30a4\u30c9\u30e9\u30a4\u30f32024\uff5c4\u7ae0\u3000\u904b\u52d5\u7642\u6cd5<\/a><br \/>\n<a href=\"https:\/\/iryogakkai.jp\/2015-69-07\/317-24.pdf\">IRYO Vol.69No.7\uff5c\u904b\u52d5\u3068\u9178\u5316\u30b9\u30c8\u30ec\u30b9\u2015\u6d3b\u6027\u9178\u7d20\u3068\u6297\u9178\u5316\u9632\u5fa1\u306e\u30d0\u30e9\u30f3\u30b9\u306e\u91cd\u8981\u6027\u2015<\/a><\/p>\n<h3><span class=\"ez-toc-section\" id=\"%E7%B4%B0%E8%83%9E%E3%82%92%E8%8B%A5%E8%BF%94%E3%82%89%E3%81%9B%E3%82%8B%E5%86%8D%E7%94%9F%E5%8C%BB%E7%99%82%E3%81%A7%E3%81%AE%E3%82%A2%E3%83%97%E3%83%AD%E3%83%BC%E3%83%81\"><\/span>\u7d30\u80de\u3092\u82e5\u8fd4\u3089\u305b\u308b\u518d\u751f\u533b\u7642\u3067\u306e\u30a2\u30d7\u30ed\u30fc\u30c1<span 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