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href=\"https:\/\/stemcells.jp\/topics\/why-fatigue-increases-with-age\/#%E7%B4%B0%E8%83%9E%E3%83%AC%E3%83%99%E3%83%AB%E3%81%8B%E3%82%89%E3%82%A2%E3%83%97%E3%83%AD%E3%83%BC%E3%83%81%E3%81%99%E3%82%8B%E5%86%8D%E7%94%9F%E5%8C%BB%E7%99%82\" title=\"\u7d30\u80de\u30ec\u30d9\u30eb\u304b\u3089\u30a2\u30d7\u30ed\u30fc\u30c1\u3059\u308b\u518d\u751f\u533b\u7642\">\u7d30\u80de\u30ec\u30d9\u30eb\u304b\u3089\u30a2\u30d7\u30ed\u30fc\u30c1\u3059\u308b\u518d\u751f\u533b\u7642<\/a><ul class='ez-toc-list-level-3'><li class='ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-7\" href=\"https:\/\/stemcells.jp\/topics\/why-fatigue-increases-with-age\/#%E5%86%8D%E7%94%9F%E5%8C%BB%E7%99%82%E3%81%A8%E3%81%AF\" title=\"\u518d\u751f\u533b\u7642\u3068\u306f\">\u518d\u751f\u533b\u7642\u3068\u306f<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-8\" href=\"https:\/\/stemcells.jp\/topics\/why-fatigue-increases-with-age\/#%E5%86%8D%E7%94%9F%E5%8C%BB%E7%99%82%E3%81%A7%E3%81%AE%E3%82%A2%E3%83%97%E3%83%AD%E3%83%BC%E3%83%81\" title=\"\u518d\u751f\u533b\u7642\u3067\u306e\u30a2\u30d7\u30ed\u30fc\u30c1\">\u518d\u751f\u533b\u7642\u3067\u306e\u30a2\u30d7\u30ed\u30fc\u30c1<\/a><\/li><\/ul><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-9\" href=\"https:\/\/stemcells.jp\/topics\/why-fatigue-increases-with-age\/#%E3%81%BE%E3%81%A8%E3%82%81\" title=\"\u307e\u3068\u3081\">\u307e\u3068\u3081<\/a><\/li><\/ul><\/nav><\/div>\n<h2><span class=\"ez-toc-section\" 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href=\"https:\/\/www.jstage.jst.go.jp\/article\/tonyobyo\/51\/4\/51_4_295\/_pdf\">\u7cd6\u5c3f\u75c5 51(4)\uff1a295\u223c297, 2008\uff5c\u30df\u30c8\u30b3\u30f3\u30c9\u30ea\u30a2\u306b\u304a\u3051\u308b\u52a0\u9f62\u5909\u5316\u3068\u7cd6\u4ee3\u8b1d<\/a><\/p>\n<h2><span class=\"ez-toc-section\" id=\"%E5%9B%9E%E5%BE%A9%E5%8A%9B%E3%82%92%E5%8F%96%E3%82%8A%E6%88%BB%E3%81%99%E3%81%9F%E3%82%81%E3%81%AE%E7%94%9F%E6%B4%BB%E7%BF%92%E6%85%A3%E3%81%8B%E3%82%89%E3%81%AE%E3%82%A2%E3%83%97%E3%83%AD%E3%83%BC%E3%83%81%EF%BD%9C%E5%AF%BE%E7%AD%96\"><\/span>\u56de\u5fa9\u529b\u3092\u53d6\u308a\u623b\u3059\u305f\u3081\u306e\u751f\u6d3b\u7fd2\u6163\u304b\u3089\u306e\u30a2\u30d7\u30ed\u30fc\u30c1\uff5c\u5bfe\u7b56<span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p>\u52a0\u9f62\u306b\u3088\u308b\u56de\u5fa9\u529b\u306e\u4f4e\u4e0b\u3092\u9632\u3050\u305f\u3081\u306b\u306f\u3001\u6bce\u65e5\u306e\u751f\u6d3b\u7fd2\u6163\u3092\u898b\u76f4\u3057\u3001\u7d30\u80de\u304c\u672c\u6765\u6301\u3064\u50cd\u304d\u3092\u30b5\u30dd\u30fc\u30c8\u3059\u308b\u3053\u3068\u304c\u91cd\u8981\u3067\u3059\u3002<\/p>\n<p>\u3053\u3053\u3067\u306f\u3001\u300c\u7761\u7720\u300d\u300c\u98df\u4e8b\u300d\u300c\u904b\u52d5\u300d\u306e3\u3064\u306e\u89b3\u70b9\u304b\u3089\u3001\u4eca\u65e5\u304b\u3089\u5b9f\u8df5\u3067\u304d\u308b\u5177\u4f53\u7684\u306a\u30a2\u30d7\u30ed\u30fc\u30c1\u3092\u3054\u7d39\u4ecb\u3057\u307e\u3059\u3002<\/p>\n<h3><span class=\"ez-toc-section\" id=\"%E8%B3%AA%E3%81%AE%E9%AB%98%E3%81%84%E7%9D%A1%E7%9C%A0\"><\/span>\u8cea\u306e\u9ad8\u3044\u7761\u7720<span 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class=\"ez-toc-section\" id=\"%E6%8A%97%E9%85%B8%E5%8C%96%E3%81%A8%E3%82%A8%E3%83%8D%E3%83%AB%E3%82%AE%E3%83%BC%E4%BB%A3%E8%AC%9D%E3%82%92%E6%84%8F%E8%AD%98%E3%81%97%E3%81%9F%E9%A3%9F%E4%BA%8B\"><\/span>\u6297\u9178\u5316\u3068\u30a8\u30cd\u30eb\u30ae\u30fc\u4ee3\u8b1d\u3092\u610f\u8b58\u3057\u305f\u98df\u4e8b<span class=\"ez-toc-section-end\"><\/span><\/h3>\n<p>\u98df\u4e8b\u3067\u306f\u3001\u30df\u30c8\u30b3\u30f3\u30c9\u30ea\u30a2\u3078\u30c0\u30e1\u30fc\u30b8\u3092\u4e0e\u3048\u308b\u6d3b\u6027\u9178\u7d20\u3078\u5bfe\u6297\u3059\u308b\u305f\u3081\u3001\u6297\u9178\u5316\u4f5c\u7528\u3092\u6301\u3064\u6804\u990a\u7d20\u3092\u7a4d\u6975\u7684\u306b\u53d6\u308a\u5165\u308c\u308b\u3053\u3068\u304c\u91cd\u8981\u3067\u3059\u3002\u30d3\u30bf\u30df\u30f3C\u3092\u8c4a\u5bcc\u306b\u542b\u3080\u91ce\u83dc\u3084\u679c\u7269\u3001\u30dd\u30ea\u30d5\u30a7\u30ce\u30fc\u30eb\u3092\u542b\u3080\u304a\u8336\u306a\u3069\u306f\u3001\u65e5\u5e38\u7684\u306b\u53d6\u308a\u5165\u308c\u3084\u3059\u3044\u98df\u54c1\u3067\u3059\u3002<\/p>\n<p>\u307e\u305f\u3001\u8c5a\u8089\u3084\u5927\u8c46\u88fd\u54c1\u306a\u3069\u306b\u591a\u304f\u542b\u307e\u308c\u308b\u30d3\u30bf\u30df\u30f3B\u7fa4\u306f\u3001\u7cd6\u8cea\u3084\u8102\u8cea\u3092\u52b9\u7387\u3088\u304f\u30a8\u30cd\u30eb\u30ae\u30fc\u3078\u5909\u63db\u3059\u308b\u305f\u3081\u306b\u6b20\u304b\u305b\u306a\u3044\u6804\u990a\u7d20\u3067\u3042\u308a\u3001\u30a8\u30cd\u30eb\u30ae\u30fc\u4ee3\u8b1d\u3092\u652f\u3048\u308b\u5f79\u5272\u304c\u3042\u308a\u307e\u3059\u3002<\/p>\n<p>\u3055\u3089\u306b\u3001\u7cd6\u8cea\u306e\u6442\u308a\u904e\u304e\u306b\u3082\u6ce8\u610f\u304c\u5fc5\u8981\u3067\u3059\u3002\u8840\u7cd6\u5024\u304c\u6025\u6fc0\u306b\u4e0a\u4e0b\u3059\u308b\u3068\u5f37\u3044\u75b2\u52b4\u611f\u3092\u62db\u304d\u3084\u3059\u304f\u306a\u308a\u307e\u3059\u3002\u307e\u305f\u3001\u52a0\u9f62\u306b\u3088\u3063\u3066\u7cd6\u8cea\u3092\u52b9\u7387\u3088\u304f\u30a8\u30cd\u30eb\u30ae\u30fc\u3078\u5909\u63db\u3059\u308b\u50cd\u304d\u3082\u4f4e\u4e0b\u3059\u308b\u305f\u3081\u3001\u98df\u4e8b\u306f\u8179\u516b\u5206\u76ee\u3092\u610f\u8b58\u3057\u3001\u6804\u990a\u30d0\u30e9\u30f3\u30b9\u306e\u53d6\u308c\u305f\u5185\u5bb9\u3092\u5fc3\u304c\u3051\u308b\u3053\u3068\u304c\u5927\u5207\u3067\u3059\u3002<\/p>\n<h3><span class=\"ez-toc-section\" id=\"%E3%83%9F%E3%83%88%E3%82%B3%E3%83%B3%E3%83%89%E3%83%AA%E3%82%A2%E3%82%92%E5%A2%97%E3%82%84%E3%81%99%E9%81%A9%E5%BA%A6%E3%81%AA%E9%81%8B%E5%8B%95\"><\/span>\u30df\u30c8\u30b3\u30f3\u30c9\u30ea\u30a2\u3092\u5897\u3084\u3059\u9069\u5ea6\u306a\u904b\u52d5<span class=\"ez-toc-section-end\"><\/span><\/h3>\n<p>\u30df\u30c8\u30b3\u30f3\u30c9\u30ea\u30a2\u306e\u6a5f\u80fd\u3092\u7dad\u6301\u3057\u3001\u305d\u306e\u6570\u3092\u5897\u3084\u3059\u305f\u3081\u306b\u306f\u3001\u9069\u5ea6\u306a\u904b\u52d5\u304c\u6709\u52b9\u3068\u3055\u308c\u3066\u3044\u307e\u3059\u3002\u305f\u3060\u3057\u3001\u904e\u5ea6\u306b\u6fc0\u3057\u3044\u904b\u52d5\u306f\u9178\u5316\u30b9\u30c8\u30ec\u30b9\u3092\u5f37\u304f\u751f\u307f\u51fa\u3057\u3001\u304b\u3048\u3063\u3066\u75b2\u52b4\u3092\u5897\u52a0\u3055\u305b\u308b\u53ef\u80fd\u6027\u304c\u3042\u308a\u307e\u3059\u3002\u305d\u306e\u305f\u3081\u3001\u7121\u7406\u306e\u306a\u3044\u8ca0\u8377\u3067\u7d99\u7d9a\u3059\u308b\u3053\u3068\u304c\u5927\u5207\u3067\u3059\u3002<\/p>\n<p>\u4f8b\u3048\u3070\u3001\u5c11\u3057\u606f\u304c\u5f3e\u3080\u7a0b\u5ea6\u306e\u65e9\u6b69\u304d\uff08\u30a6\u30a9\u30fc\u30ad\u30f3\u30b0\uff09\u30921\u65e520\u301c30\u5206\u7a0b\u5ea6\u7d99\u7d9a\u3059\u308b\u3053\u3068\u3067\u3001\u9aa8\u683c\u7b4b\u5185\u306e\u30df\u30c8\u30b3\u30f3\u30c9\u30ea\u30a2\u91cf\u304c\u5897\u52a0\u3057\u3001\u7d30\u80de\u306e\u30a8\u30cd\u30eb\u30ae\u30fc\u7523\u751f\u80fd\u529b\u306e\u5411\u4e0a\u304c\u671f\u5f85\u3055\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n<p>\u307e\u305f\u3001\u4e0b\u534a\u8eab\u306e\u5927\u304d\u306a\u7b4b\u8089\u3092\u52d5\u304b\u3059\u8efd\u3044\u30b9\u30af\u30ef\u30c3\u30c8\u3082\u304a\u3059\u3059\u3081\u3067\u3059\u3002\u7b4b\u8089\u3092\u52d5\u304b\u3059\u3053\u3068\u3067\u8840\u6d41\u304c\u6539\u5584\u3057\u3001\u75b2\u52b4\u7269\u8cea\u306e\u6392\u51fa\u3092\u4fc3\u3059\u3053\u3068\u304c\u671f\u5f85\u3055\u308c\u308b\u307b\u304b\u3001\u65e5\u5e38\u751f\u6d3b\u306b\u5fc5\u8981\u306a\u7b4b\u529b\u306e\u7dad\u6301\u306b\u3082\u5f79\u7acb\u3061\u307e\u3059\u3002<\/p>\n<p>\u51fa\u5178\uff1a<a href=\"https:\/\/www.jssr.jp\/basicofsleepdisorders7\">\u65e5\u672c\u7761\u7720\u5b66\u4f1a\uff5c\u9ad8\u9f62\u8005\u306e\u7761\u7720\u969c\u5bb3<\/a><\/p>\n<p>\u51fa\u5178\uff1a<a href=\"https:\/\/niconurs.repo.nii.ac.jp\/record\/541\/files\/70009-015.pdf\">\u65b0\u6f5f\u770c\u7acb\u770b\u8b77\u5927\u5b66\uff5c\u6d3b\u6027\u9178\u7d20\u3092\u6d88\u53bb\u3059\u308b\u6297\u9178\u5316\u7269\u8cea\u3067\u3042\u308b\u304a\u8336\u985e\u306e\u6297\u9178\u5316\u80fd\u6bd4\u8f03<\/a><\/p>\n<p>\u51fa\u5178\uff1a<a href=\"https:\/\/iryogakkai.jp\/2015-69-07\/317-24.pdf\">IRYO Vol.69 No.7\uff5c\u904b\u52d5\u3068\u9178\u5316\u30b9\u30c8\u30ec\u30b9\u2015\u6d3b\u6027\u9178\u7d20\u3068\u6297\u9178\u5316\u9632\u5fa1\u306e\u30d0\u30e9\u30f3\u30b9\u306e\u91cd\u8981\u6027\u2015<\/a><\/p>\n<p>\u51fa\u5178\uff1a<a href=\"https:\/\/www.semanticscholar.org\/paper\/Biochemical-adaptations-in-muscle.-Effects-of-on-in-Holloszy\/c765ea9d46775e212d0e3bfac77d2acd4b313b15\">Biochemical adaptations in muscle. Effects of exercise on mitochondrial oxygen uptake and respiratory enzyme activity in skeletal muscle.<\/a><\/p>\n<h2><span class=\"ez-toc-section\" id=\"%E7%B4%B0%E8%83%9E%E3%83%AC%E3%83%99%E3%83%AB%E3%81%8B%E3%82%89%E3%82%A2%E3%83%97%E3%83%AD%E3%83%BC%E3%83%81%E3%81%99%E3%82%8B%E5%86%8D%E7%94%9F%E5%8C%BB%E7%99%82\"><\/span>\u7d30\u80de\u30ec\u30d9\u30eb\u304b\u3089\u30a2\u30d7\u30ed\u30fc\u30c1\u3059\u308b\u518d\u751f\u533b\u7642<span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p>\u751f\u6d3b\u7fd2\u6163\u306e\u6539\u5584\u306b\u52a0\u3048\u3001\u8fd1\u5e74\u3067\u306f\u7d30\u80de\u305d\u306e\u3082\u306e\u3078\u50cd\u304d\u304b\u3051\u308b\u518d\u751f\u533b\u7642\u3082\u65b0\u305f\u306a\u9078\u629e\u80a2\u3068\u3057\u3066\u6ce8\u76ee\u3055\u308c\u3066\u3044\u307e\u3059\u3002\u6804\u990a\u30c9\u30ea\u30f3\u30af\u3084\u30b5\u30d7\u30ea\u30e1\u30f3\u30c8\u306a\u3069\u306b\u3088\u308b\u4e00\u6642\u7684\u306a\u75b2\u52b4\u5bfe\u7b56\u3068\u306f\u7570\u306a\u308a\u3001\u52a0\u9f62\u306b\u3088\u3063\u3066\u6a5f\u80fd\u304c\u4f4e\u4e0b\u3057\u305f\u7d30\u80de\u3078\u76f4\u63a5\u30a2\u30d7\u30ed\u30fc\u30c1\u3059\u308b\u3053\u3068\u3092\u76ee\u7684\u3068\u3057\u305f\u6cbb\u7642\u6cd5\u3067\u3059\u3002<\/p>\n<h3><span class=\"ez-toc-section\" id=\"%E5%86%8D%E7%94%9F%E5%8C%BB%E7%99%82%E3%81%A8%E3%81%AF\"><\/span>\u518d\u751f\u533b\u7642\u3068\u306f<span 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