KNEE CARTILAGE REGENERATION

Knee cartilage can be expected to regenerate using stem cells.
(Photo on the right: Cartilage regenerates like hair.)

Details of the above photo (based on Medical Affairs Notification 0508 No. 1, May 8, 2018)
[Disease] Osteoarthritis and osteonecrosis of the right knee [Age/Gender] 45-year-old male
[Procedure] Injection of 100 million stem cells
[Procedure description] After administering local anesthesia, stem cells are injected into the knee joint cavity with a needle.
[Side effects (risks) of the procedure] Local redness, swelling, pain, and in rare cases, allergic reactions may occur.
[Procedure price] 1 million yen (excluding tax) (as of August 2018) (as of July 2020: 498,000 yen excluding tax)

KNEE CARTILAGE REGENERATION

Do you have any of these problems?


I don't want to get an artificial joint if possible.


Please contact us before considering an artificial joint

The effect of the injection
does not last long.

Rather than continuing with hyaluronic acid injections,
why not consider regenerating knee cartilage with stem cells?

Due to his age, surgery is not possible and
there is no treatment available

No complicated surgery is required and
the number of visits to the hospital is minimal.

STEM CELL

With “autologous adipose stem cell treatment”, you can expect to solve your worries.

of stem cells
?

Our stem cells and stem cell extracts are cultivated under strict management and strict hygiene checks
. Our CPC (cell culture facility) has obtained quality management system certification (ISO 9001). Furthermore, stem cell therapy involves culturing and administering the patient's own stem cells. This means that the risk of rejection after administration is extremely low.


8,000 cases of cultured stem cell therapy

Our in-house stem cell culture room
utilizes our experience in culturing stem cells at our facilities to provide cultured stem cell therapy.

* Our group research (March 2015-January 2020)

What are the risks of stem cells?

Our stem cells and stem cell extracts are cultivated under strict management and strict hygiene checks
. Our CPC (cell culture facility) has obtained quality management system certification (ISO 9001). Furthermore, stem cell therapy involves culturing and administering the patient's own stem cells. This means that the risk of rejection after administration is extremely low.

Cultured stem cell therapy 8,000 cases

Our in-house stem cell culture room
utilizes our experience in culturing stem cells at our facilities to provide cultured stem cell therapy.

* Our group research (March 2015-January 2020)

Before giving up on artificial joints, please contact us!

CONTACTFor
knee problems, please contact us here

TEL: 03-3400-2277
Hours: 10:00 - 19:00 (Monday, Tuesday, Thursday, Friday, Saturday, and public holidays)

KNEE CARTILAGE REGENERATION

Do you have any of these problems?

Expected to regenerate knee cartilage itself,
greatly reducing pain

No need for hospitalization or knee incision Stem cell extract ingredients and stem cells are administered by injection

No need for regular visits to the hospital.
Treatment can be completed in as few as two visits.

What are the effects of stem cells? Stem cells suppress inflammation in joints and promote repair and regeneration of cartilage, which can be expected to regenerate joint structures and reduce pain. Stem cells are also effective in repairing damaged ligaments and muscles, so top athletes overseas are receiving treatment.

The "components" secreted from stem cells have the same regenerative and repairing effects as stem cells. Its components are much smaller in size than stem cells, so it is possible to reach the details of the body and promote tissue regeneration.

Cell culture In our laboratory, we have introduced the latest equipment, and we have established a system for operating and managing cell culture, implementing strict quality control, such as managing all processes. The patient's autologous stem cells can be cultured in the hospital's laboratory.

A license is required to provide regenerative medicine In order to provide regenerative medicine, based on the Act on Ensuring the Safety of Regenerative Medicine, a specific authorized regenerative medicine committee has It must be reviewed by the Ministry of Health, Labor and Welfare and accepted by the Ministry of Health, Labor and Welfare. Our hospital is a medical institution that has been accepted by the Ministry of Health, Labor and Welfare for a provision plan for knee joint stem cell administration.

PROLIFERATION

Stem cell culture at our hospital

Cultured stem cell therapy added to the options. Please consider this for your knee pain.

Regenerative medicine is a treatment that uses a patient's own cells to promote the recovery of bodily functions in response to diseases caused by some kind of damage to tissues or organs.
Stem cells, which are responsible for the development and regeneration of tissues, have the ability to recreate and replenish somatic cells that decrease with age, and are applied in the field of regenerative medicine.
At our clinic, we cultivate the patient's own stem cells in a state-of-the-art laboratory operated under strict hygiene control, and administer them directly to the knee joint.
This is a new treatment that alleviates damage to knee cartilage without the need for difficult surgery or frequent injections.
If you are suffering from osteoarthritis of the knee, please feel free to consult us.
Director of Omotesando Helene Clinic

Nana Kobayashi

Before giving up on artificial joints, please contact us!

CONTACTFor
knee problems, please contact us here

TEL: 03-3400-2277
Hours: 10:00 - 19:00 (Monday, Tuesday, Thursday, Friday, Saturday, and public holidays)

CONTACTFor
knee problems, please contact us here

TEL: 03-3400-2277
Hours: 10:00 - 19:00 (Monday, Tuesday, Thursday, Friday, Saturday, and public holidays)

Q&A

FAQ

Q: Do I need to be hospitalized?

A: No. It is not necessary.
Stem cells will be collected during your first visit. They will be administered during your second visit. However, a four-week cell culture period is required between the collection of stem cells and administration.

Q: How painful is the treatment?

A: Skin sampling can be done under local anesthesia, so please consider it as a dentist's treatment. The skin to be collected is about 5 mm, and after a month it has become so familiar that you can't even tell where it was taken.

Q: How long does it take to take effect?

A: There are large individual differences in the effectiveness of stem cell therapy, but please consider 3 to 6 months as a guideline.

QIs stem cell therapy covered by insurance?

A: Since it is a free medical treatment, the full amount will be borne by the patient.

Q: Where are stem cells located?

A: Stem cells are present throughout the body. We think that patients have a strong resistance to collecting fat by fat absorption, so at our clinic, we use a skin punch to collect fat.

Q: Is the treatment nationally licensed?

A: Based on the Act on the Safety of Regenerative Medicine, treatments that have been reviewed and approved by a third-party committee are accepted as treatment plans by the Ministry of Health, Labour and Welfare.
Our group is a medical institution whose provision plan for intra-articular stem cell injection into the knee joint has been accepted by the Ministry of Health, Labour and Welfare.

Q: Are medical expenses deductible?

A: If it is for medical treatment, it may be eligible for medical expense deduction. Please contact your nearest tax office for details on how to proceed. Please keep the receipt issued by our hospital in a safe place.

PLAN

Treatment cost for intra-articular knee injection

treatment of one knee

* Stem cell extraction components can be administered to the knee on the day of consultation. *Cultured stem cells can also be administered. Please feel free to consult your doctor.

Stem cells (100 million cells)
1,078,000 yen (tax included)

*Stem cells are cultured in our laboratory. Approximately 100 million cells from one knee are cultured. *The price includes consultation fee, blood test fee, cell collection fee, administration fee, culture fee, and storage fee.

treatment of both knees

* Stem cell extraction components can be administered to the knee on the day of consultation. *Cultured stem cells can also be administered. Please feel free to consult your doctor.

Stem cells (100 million cells x both knees)
1,485,000 yen (tax included)

*Stem cells are cultured in our laboratory. Approximately 100 million cells from one knee are cultured. *The price includes consultation fee, blood test fee, cell collection fee, administration fee, culture fee, and storage fee.

treatment of one knee

Stem cells (100 million cells) ¥1,078,000
(tax included)
  • *Stem cells are cultured in our laboratory. Approximately 100 million cells from one knee are cultured.
  • *The price includes consultation fee, blood test fee, cell collection fee, administration fee, culture fee, and storage fee.

treatment of both knees

Stem cells (100 million cells x both knees) 1,485,000 yen
(tax included)
  • *Stem cells are cultured in our laboratory. Approximately 100 million cells from one knee are cultured.
  • *The price includes consultation fee, blood test fee, cell collection fee, administration fee, culture fee, and storage fee.

What is the appropriate number of cells for me?

The appropriate number of cells per knee is thought to be around 100 million worldwide.
In Japan, regenerative medicine clinics generally use 20 million to 100 million cells per knee.
Our clinic uses 100 million cells per knee.

About medical expense deduction

Treatment costs at our hospital may be subject to the medical expense deduction system.
Please keep your receipts in a safe place.
For details on procedures, please contact your nearest tax office.
*Example of how to fill out your tax return

CLINIC & DOCTOR INTRODUCTION

Clinic doctor introduction

Omotesando Helene Clinic Knee Arthritis Outpatient

【Consultation hours】 10:00 〜 19:00

[Telephone reservation] Monday, Tuesday, Wednesday, Thursday, Friday, Saturday, holidays

【Closed days】 Wednesday · Sunday

【Address】〒 107-0062

  5-9-15 Minami Aoyama, Minato-ku, Tokyo Aoyama OHMOTO Building 3F

[Phone number] 03-3400-2277


Takaaki Matsuoka HELENE Group Representative

Dr. Matsuoka Takaaki

[Career]

2003 Graduated from Keio University School of Medicine 

Department of Anesthesiology, Keio University Hospital
2004 Department of Anesthesiology and Intensive Care Unit, Keiyukai Keiyu Hospital
2005 Joined Medical Corporation Shobikai
2009 Served as Vice President of Medical Corporation Shobikai
2013 Founded Rene Clinic in Omotesando

[Affiliated academic societies, etc.]

・PGA member of Harvard Medical School
・Executive MBA from Peking University
・Specialist of the Japanese Society of Aesthetic Plastic
Surgery ・Ministry of Health, Labor and Welfare certified anesthesiologist
・Japanese Society of Anesthesiologists certified anesthesiologist

【paper】

Conference presentations and papers (ORCID)

Nana Kobayashi, Director

Dr. Nana Kobayashi

[Career]

March 2007 Graduated from Nihon University School of Medicine (Doctor's License Number: 461258)
April 2007 - March 2010 Nihon University School of Medicine Itabashi Hospital
April 2010 - April 2011 Public Showa Hospital, Gastrointestinal Surgery
May 2011 - March 2012 Nihon University Nerima Hikarigaoka Hospital, Gastrointestinal Surgery
April 2013 - March 2015 Sakura General Hospital, Gastrointestinal Surgery
April 2015 - April 2021 Vice Director of Jiyugaoka Medical Plaza, Gastroenterology
May 1, 2021 - Present

[Affiliated academic societies, etc.]

・Gastrointestinal Surgery Society
・Gastroenterology Society
・Abdominal Emergency Surgery Society

Dr. Shinichiro Iwata

Dr. Shinichiro Iwata

[Career]

1996 Graduated from Keio University School of Medicine
~ 2001 Worked at Keio University affiliated hospitals
(Ashikaga Red Cross Hospital, Odawara Municipal Hospital,
Ise Keio Hospital, Hino Municipal Hospital)
2004 Studied abroad at STANFORD University
2006 National Hospital Organization Murayama Medical Center
2009 Established NPO Back Pain and Knee Pain Team Medical Research Institute
2016 Omotesando Helene Clinic Knee Joint Regenerative Medicine

[Affiliated academic societies, etc.]

・Japanese Orthopaedic Association
・Japanese Knee Society

​Family members can also consult, so please feel free to contact us.

CONTACTFor
knee problems, please contact us here

TEL: 03-3400-2277
Hours: 10:00 - 19:00 (Monday, Tuesday, Thursday, Friday, Saturday, and public holidays)

CONTACTFor
knee problems, please contact us here

TEL: 03-3400-2277
Hours: 10:00 - 19:00 (Monday, Tuesday, Thursday, Friday, Saturday, and public holidays)