KNEE CARTILAGE REGENERATION

Knee cartilage can be regenerated using stem cells.
(Right photo: Cartilage regenerating like hair)

The above photo is detailed (based on Medical Affairs Notification No. 0508-1, May 8, 2018):
[Diagnosis] Osteoarthritis and osteonecrosis of the right knee [Age/Sex] 45-year-old male
[Procedure] Administration of 100 million stem cells
[Procedure Description] After local anesthesia, stem cells are injected into the knee joint cavity using a needle.
[Side Effects (Risks)] Local redness, swelling, pain, and rarely, allergic reactions may occur.
[Procedure Price] 1,000,000 yen

KNEE CARTILAGE REGENERATION

Do you have any of these problems?

have an artificial joint.
prefer not to

Before considering artificial joint replacement,
please feel free to consult with us.

The effects of the injection didn't last,
and the situation wasn't improving.

Instead of continuing with hyaluronic acid injections,
why not consider regenerating knee cartilage with stem cells?

Due to age, surgery is not possible and
there are no other treatment options.

It does not require complex surgery, and
the number of visits to the clinic is kept to a minimum.

STEM CELL

With “autologous adipose stem cell treatment”, you can expect to solve your worries.

of stem cells
?

Our stem cells and stem cell extracts are cultured under strict control and rigorous hygiene checks
. Our CPC (Cell Processing Center) is certified under the ISO 9001 Quality Management System standard. Furthermore, in stem cell therapy, we culture and administer the patient's own stem cells. Therefore, the risk of rejection after administration is extremely low.

cultured stem cell therapy
8,000 cases of

Our hospital's in-house stem cell culture laboratory
utilizes our experience in culturing stem cells within our own facilities to provide cultured stem cell therapy.

* Our group research (March 2015-January 2020)

What are the risks of stem cells?

Our stem cells and stem cell extracts are cultured under strict control and rigorous hygiene checks
. Our CPC (Cell Processing Center) is certified under the ISO 9001 Quality Management System standard. Furthermore, in stem cell therapy, we culture and administer the patient's own stem cells. Therefore, the risk of rejection after administration is extremely low.

Cultured stem cell therapy 8,000 cases

Our hospital's in-house stem cell culture laboratory
utilizes our experience in culturing stem cells within our own facilities to provide cultured stem cell therapy.

* Our group research (March 2015-January 2020)

Before giving up on artificial joints, please contact us!

CONTACT:
For consultations regarding knee problems, please click here.

TEL: 03-3400-2277
Hours: 10:00 - 19:00 (Monday, Tuesday, Thursday, Friday, Saturday, and public holidays)

KNEE CARTILAGE REGENERATION

Do you have any of these problems?

Expected to regenerate the knee cartilage itself,
significantly reducing pain.

No need for hospitalization or knee incision Stem cell extract ingredients and stem cells are administered by injection

No need for regular hospital visits;
treatment can be completed in as few as two visits.

What are the effects of stem cells? Stem cells suppress inflammation in joints and promote repair and regeneration of cartilage, which can be expected to regenerate joint structures and reduce pain. Stem cells are also effective in repairing damaged ligaments and muscles, so top athletes overseas are receiving treatment.

The "components" secreted from stem cells have the same regenerative and repairing effects as stem cells. Its components are much smaller in size than stem cells, so it is possible to reach the details of the body and promote tissue regeneration.

Cell culture In our laboratory, we have introduced the latest equipment, and we have established a system for operating and managing cell culture, implementing strict quality control, such as managing all processes. The patient's autologous stem cells can be cultured in the hospital's laboratory.

A license is required to provide regenerative medicine In order to provide regenerative medicine, based on the Act on Ensuring the Safety of Regenerative Medicine, a specific authorized regenerative medicine committee has It must be reviewed by the Ministry of Health, Labor and Welfare and accepted by the Ministry of Health, Labor and Welfare. Our hospital is a medical institution that has been accepted by the Ministry of Health, Labor and Welfare for a provision plan for knee joint stem cell administration.

PROLIFERATION

Stem cell culture at our hospital

Cultured stem cell therapy added to the options. Please consider this for your knee pain.

Regenerative medicine is a treatment method that uses the patient's own cells to promote the recovery of bodily functions in cases of diseases caused by damage to tissues or organs.
Stem cells, which are responsible for the development and regeneration of tissues, have the ability to generate and replenish somatic cells that decrease with age, and are being applied in the field of regenerative medicine.
At our clinic, we culture the patient's own stem cells in a state-of-the-art laboratory operating under strict hygiene control and administer them directly to the knee joint.
This is a new therapy that alleviates knee cartilage damage without the need for complicated surgery or frequent injections.
If you are suffering from osteoarthritis of the knee, please feel free to consult with us.
Director, Omotesando Helene Clinic

Nana Kobayashi

Before giving up on artificial joints, please contact us!

CONTACT:
For consultations regarding knee problems, please click here.

TEL: 03-3400-2277
Hours: 10:00 - 19:00 (Monday, Tuesday, Thursday, Friday, Saturday, and public holidays)

CONTACT:
For consultations regarding knee problems, please click here.

TEL: 03-3400-2277
Hours: 10:00 - 19:00 (Monday, Tuesday, Thursday, Friday, Saturday, and public holidays)

Q&A

FAQ

Q: Do I need to be hospitalized?

A: No, it's not necessary.
Stem cell collection will take place during your first visit, and the stem cell administration will take place during your second visit. However, a 4-week cell culture period is required between stem cell collection and administration.

Q: How painful is the treatment?

A: Skin sampling can be done under local anesthesia, so please consider it as a dentist's treatment. The skin to be collected is about 5 mm, and after a month it has become so familiar that you can't even tell where it was taken.

Q: How long does it take to take effect?

A: There are large individual differences in the effectiveness of stem cell therapy, but please consider 3 to 6 months as a guideline.

QIs stem cell therapy covered by insurance?

A: Since it is a free medical treatment, the full amount will be borne by the patient.

Q: Where are stem cells located?

A: Stem cells are present throughout the body. We think that patients have a strong resistance to collecting fat by fat absorption, so at our clinic, we use a skin punch to collect fat.

Q: Is the treatment nationally licensed?

A: Based on the Act on Ensuring the Safety of Regenerative Medicine, treatments that have been reviewed and approved by a third-party committee are accepted by the Ministry of Health, Labour and Welfare as treatment plans.
Our group is a medical institution whose provision plan for intra-articular stem cell administration of knee joints has been accepted by the Ministry of Health, Labour and Welfare.

Q: Are medical expenses deductible?

A: If it is for medical treatment, it may be eligible for medical expense deduction. Please contact your nearest tax office for details on how to proceed. Please keep the receipt issued by our hospital in a safe place.

PLAN

Treatment cost for intra-articular knee injection

treatment of one knee

* Stem cell extraction components can be administered to the knee on the day of consultation. *Cultured stem cells can also be administered. Please feel free to consult your doctor.

Stem cells (100 million cells):
1,078,000 yen (tax included)

*Stem cells are cultured in our laboratory. Approximately 100 million cells from one knee are cultured. *The price includes consultation fee, blood test fee, cell collection fee, administration fee, culture fee, and storage fee.

treatment of both knees

* Stem cell extraction components can be administered to the knee on the day of consultation. *Cultured stem cells can also be administered. Please feel free to consult your doctor.

Stem cells (100 million cells x both knees):
1,485,000 yen (tax included)

*Stem cells are cultured in our laboratory. Approximately 100 million cells from one knee are cultured. *The price includes consultation fee, blood test fee, cell collection fee, administration fee, culture fee, and storage fee.

treatment of one knee

Stem cells (100 million cells) ¥1,078,000
(tax included)
  • *Stem cells are cultured in our laboratory. Approximately 100 million cells from one knee are cultured.
  • *The price includes consultation fee, blood test fee, cell collection fee, administration fee, culture fee, and storage fee.

treatment of both knees

Stem cells (100 million cells x both knees) 1,485,000 yen
(tax included)
  • *Stem cells are cultured in our laboratory. Approximately 100 million cells from one knee are cultured.
  • *The price includes consultation fee, blood test fee, cell collection fee, administration fee, culture fee, and storage fee.

What is the appropriate number of cells for me?

The appropriate number of cells for each knee is generally considered to be around 100 million worldwide.
In Japanese regenerative medicine clinics, 20 million to 100 million cells per knee is common.
Our clinic uses 100 million cells per knee.

About medical expense deduction

Treatment costs at our hospital may be eligible for medical expense deductions.
Please keep your receipts safe.
 For details on the procedure, please contact your nearest tax office.
*Example of how to fill out the tax return form

CLINIC & DOCTOR INTRODUCTION

Clinic doctor introduction

Omotesando Helene Clinic Knee Arthritis Outpatient

【Consultation hours】 10:00 〜 19:00

[Telephone reservation] Monday, Tuesday, Wednesday, Thursday, Friday, Saturday, holidays

【Closed days】 Wednesday · Sunday

【Address】〒 107-0062

  5-9-15 Minami Aoyama, Minato-ku, Tokyo Aoyama OHMOTO Building 3F

[Phone number] 03-3400-2277


Takaaki Matsuoka HELENE Group Representative

Dr. Matsuoka Takaaki

[Career]

2003 Graduated from Keio University School of Medicine 

Keio University Hospital Anesthesiology Department
(2004) Keiyukai Keiyu Hospital Anesthesiology Department/Intensive Care Unit
(2005) Joined Medical Corporation Shobikai
(2009) Served as General Vice Director of Medical Corporation Shobikai
(2013) Founded Omotesando Helene Clinic

[Affiliated academic societies, etc.]

- Member of the PGA Program at Harvard Medical School
- Executive MBA from Peking University
- Board Certified Plastic Surgeon of the Japanese Society of Aesthetic Plastic
Surgery - Certified Anesthesiologist by the Ministry of Health, Labour and Welfare
- Certified Anesthesiologist by the Japanese Society of Anesthesiologists

【paper】

Conference presentations and papers (ORCID)

Nana Kobayashi, Director

Dr. Nana Kobayashi

[Career]

March 2007: Graduated from Nihon University School of Medicine (Medical License Number: 461258)
April 2007 - March 2010: Itabashi Hospital, Nihon University School of Medicine
April 2010 - April 2011: Department of Gastroenterological Surgery, Public Showa Hospital
May 2011 - March 2012: Department of Gastroenterological Surgery, Nihon University Nerima Hikarioka Hospital
April 2013 - March 2015: Department of Gastroenterological Surgery, Sakura General Hospital
April 2015 - April 2021: Vice Director, Department of Gastroenterology, Jiyugaoka Medical Plaza
May 1, 2021 - Present

[Affiliated academic societies, etc.]

・Gastrointestinal Surgery Society
・Gastroenterology Society
・Abdominal Emergency Surgery Society

Dr. Shinichiro Iwata

Dr. Shinichiro Iwata

[Career]

1996 Graduated from Keio University School of Medicine
~ 2001 Worked at Keio University affiliated hospitals
(Ashikaga Red Cross Hospital, Odawara Municipal Hospital,
Ise Keio Hospital, Hino Municipal Hospital)
2004 Studied at Stanford University
2006 National Hospital Organization Murayama Medical Center
2009 Established NPO Low Back Pain and Knee Pain Team Medical Research Institute
2016 Omotesando Helene Clinic Knee Joint Regenerative Medicine

[Affiliated academic societies, etc.]

Japanese Orthopaedic Association
/ Japanese Knee Society

​Family members can also consult, so please feel free to contact us.

CONTACT:
For consultations regarding knee problems, please click here.

TEL: 03-3400-2277
Hours: 10:00 - 19:00 (Monday, Tuesday, Thursday, Friday, Saturday, and public holidays)

CONTACT:
For consultations regarding knee problems, please click here.

TEL: 03-3400-2277
Hours: 10:00 - 19:00 (Monday, Tuesday, Thursday, Friday, Saturday, and public holidays)