HELENE CLINIEC
TOKYO Helene AO ​​Building Clinic DUBAI DUBAI DUBAI ABU DHABI
TOKYO Helene AO ​​Building Clinic DUBAI EDINBUGH DUBAI ABU DHABI
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List of diseases

Diseases for which administration of mesenchymal stem cells is effective

Arteriosclerosis Diabetes immunosuppression knee pain periodontal disease hair regeneration skin regeneration type 1 diabetes Female hormone imbalance (menopause) neurodegenerative diseases male erectile dysfunction Senile skin changes
Professor of Clinical Microbiology, University of Cambridge
Professor Ravindra Gupta

Professor Gupta leads the Gupta Laboratory which has extensively studied HIV drug resistance at both the molecular and population levels. He has contributed to the assessment of the global scale of drug resistance. The group's work has also extended to the study of HIV reservoirs in cells, especially macrophages. This understanding is relevant both to the anatomical compartment in which HIV viral replication occurs in macrophages and to the design of strategies to treat HIV. The Gupta Lab is located in the United Kingdom and Durban, South Africa, and collaborates with the African Institute of Health Research.

In March 2019, Gupta led a team for an investigation of HIV-positive patients with Hodgkin lymphoma who have progressed after "unrelated" stem cell transplantation. It was reported that this London Patient's patients' HIV remission was demonstrated.

Career

  • Professor of Clinical Microbiology, Institute of Immunology and Infectious Disease Treatment, University of Cambridge
  • Members of the African Health Research Institute in Durban, South Africa
  • Selected as one of Time Magazine's ``100 Most Influential People of 2020''
  • Selected as "The World's Most Influential Microbiologist" in 2022
For the full version of the video, go to the next slide »
Cutting-edge technology and innovative approaches to MSC culture at Helene Clinic

Ravindra Gupta, Distinguished Professor of Microbiology and Infectious Diseases at the University of Cambridge, shared his insights into the potential of stem cells at the Helen Clinic.

In a special interview, Mr. Gupta spoke about the challenges and opportunities associated with culturing large quantities of MSCs (mesenchymal stem cells), emphasizing the importance of maintaining purity and remaining vigilant throughout the process. He praised Hellene Clinic's efforts to achieve the culture of 2.25 billion MSCs, particularly the multilayer culture flasks, specialized "Helene Growth Medium" and strict quality to ensure pure MSCs reach patients. Emphasis was placed on a combination of management measures.

Addressing concerns about tumor formation, Gupta reassured that due to stem cells' strict self-regulatory mechanisms, the risk of stem cells developing into cancer cells is minimal and may even reduce the risk of cancer development. I let it happen.

Regarding the use of exosomes, Mr. Gupta expressed enthusiasm about their therapeutic potential. He emphasized the importance of exosomes in signal transduction and reducing inflammation, and noted the compatibility of exosomes across different patients with minimal immune detection. Mr. Gupta also praised Helene Clinic's rigorous purification and testing methods for exosomes, which ensure quality and efficacy. He discussed the possibility of combining mesenchymal stem cell therapy with exosomes and envisioned a synergistic effect that could enhance therapeutic outcomes.

Overall, the esteemed professor at the University of Cambridge praised the Helene Clinic's cutting-edge technology and innovative approach, confirming that it is at the forefront of stem cell therapy research and application.

Professor of Clinical Microbiology, University of Cambridge
Professor Ravindra Gupta

Professor Gupta leads the Gupta Laboratory which has extensively studied HIV drug resistance at both the molecular and population levels. He has contributed to the assessment of the global scale of drug resistance. The group's work has also extended to the study of HIV reservoirs in cells, especially macrophages. This understanding is relevant both to the anatomical compartment in which HIV viral replication occurs in macrophages and to the design of strategies to treat HIV. The Gupta Lab is located in the United Kingdom and Durban, South Africa, and collaborates with the African Institute of Health Research.

In March 2019, Gupta led a team for an investigation of HIV-positive patients with Hodgkin lymphoma who have progressed after "unrelated" stem cell transplantation. It was reported that this London Patient's patients' HIV remission was demonstrated.

Career

  • Professor of Clinical Microbiology, Institute of Immunology and Infectious Disease Treatment, University of Cambridge
  • Members of the African Health Research Institute in Durban, South Africa
  • Selected as one of Time Magazine's ``100 Most Influential People of 2020''
  • Selected as "The World's Most Influential Microbiologist" in 2022
*For the full version of the video, go to the next slide
Helene Clinic's cutting-edge technology and innovative approaches on MSC cultivation

Cambridge University's renowned professor in microbiology and infectious diseases, Ravindra Gupta, shared his insights on the potential of Helene's stem cells.

In a special interview, Gupta discussed the challenges and opportunities associated with culturing large quantities of MSCs (Mesenchymal Stem Cells), emphasizing the importance of maintaining purity and vigilance throughout the process. He commended Helene Clinic's efforts to achieve a cultivation of 22.5 billion MSCs, particularly highlighting the combination of multi-layered culture flasks, specialized "Helene growth medium," and stringent quality control measures to ensure the delivery of pure MSCs to patients.

Addressing concerns about tumor formation, Gupta infantred that due to the strict self-regulatory mechanisms of stem cells, the risk of them developing into cancer cells is minimal, and they may even reduce the risk of cancer occurrence.

Regarding the use of exosomes, Gupta expressed enthusiasm for their therapeutic potential. He emphasized the importance of exosomes in signal transduction and reducing inflammation, noting their compatibility across different patients due to minimal immune detection. Gupta also praised Helene Clinic's rigorous purification and testing methods for exosomes, ensuring quality and efficacy. He discussed the possibility of combining mesenchymal stem cell therapy with exosomes and envisioned a synergistic effect that could enhance treatment outcomes.

Overall, Cambridge University's esteemed professor recommended Helene Clinic for its cutting-edge technology and innovative approaches, confirming its position at the forefront of stem cell therapy research and application.

TOPICS

  • blood pressure

What is vascular aging? Why does blood flow decline with age?

Many ailments seen in middle-aged and older men, such as "persistent stiff shoulders," "cold hands and feet," "difficulty concentrating," and "erectile dysfunction (ED)," may be related to decreased blood flow due to aging of blood vessels. Blood plays a vital role in delivering oxygen and nutrients to cells throughout the body, and the state of blood flow is essential for maintaining health. This article explains the mechanisms of changes in blood vessels and blood flow that occur with aging, lifestyle habits to maintain vascular health, and the possibilities of regenerative medicine. Is vascular age not the same as actual age? The mechanism of arteriosclerosis and decreased blood flow Blood vessels deliver oxygen and nutrients to cells throughout the body through the blood. However, with age, blood vessels not only lose elasticity and harden, but also..
2026/06/30
  • Diabetes

Bone marrow-derived cell therapy may reduce the risk of long-term complications in type 2 diabetes

A Novel Regenerative Medicine Approach to Diabetes Treatment Type 2 diabetes (T2DM) continues to increase worldwide, making not only blood glucose control but also the prevention of chronic complications such as cardiovascular disease and neuropathy crucial challenges. In recent years, the anti-inflammatory and tissue repair effects of bone marrow-derived mesenchymal stem cells (MSCs) have attracted attention in the field of regenerative medicine, and long-term therapeutic effects in diabetic patients are expected. This study investigated the long-term effectiveness of cell therapy using a combination of MSCs and bone marrow mononuclear cells (MCs). Long-term follow-up study over 8 years In this study, type 2 diabetes patients were divided into two groups: one group received combination therapy with MSCs and MCs in addition to standard treatment, and the other group received MCs alone
2026/06/04
  • Stem cell therapy
  • regenerative medicine

Potential of MSC-derived exosome therapy for spinal cord injury – from a Phase I clinical trial

HELENE CLINIC Academic Paper Abstract Series: Safety and potential effects of intrathecal injection of allogeneic human umbilical cord mesenchymal stem cell-derived exosomes in complete subacute spinal cord injury | Stem Cell Res Ther | 2024 Aug 26 | Akhlaghpasand M et al. Abstract (Japanese translation of Abstract) Objective
2026/06/01

Multilingual support(interpreters on staff)

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Japanese
50 people
Chinese
18 people
English
16 people
Minnan language
5 people
Indonesian
2 people
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Korean
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Mongolian
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German
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STEMCELL 

Stem cell therapy

Stem cells are cells with the ability of re-activating weakened cells and increasing

number of cells that are important to our body function but decreasing every day.

What is a stem cell?  

The mechanism of mesenchymal stem cell treatment  

Indications  

The risks of stem cell therapy  

Research papers  

academic activities 

Award

Recognized globally for excellence, we hold numerous certifications and
awards, reinforcing trust in our innovative solutions.

ISO9001 certificate
G-CERTi 2018 ISO 9001:2015
Quality Management Systems
Image of Springer Nature Reviewer Certificate
Springer Nature 2024 Biomarker Research
Reviewer Certificate
Images of European Association for Quality Research ESQR 2025
ESQR 2025 Quality Choice Prize
European Society for Quality Research ESQR images
ESQR 2024 Quality Achievements Awards
ABRM certified clinic images
ABRM 2024 Exclusive Certification
Agency in Japan
GCR certificate image
GCR 2017 International Certification
Images from Top Regenerative Medicine Solution Provider in APAC 2025
MEDTECH Outlook 2025 Top Regenerative Medicine
Solution Provider in APAC

LICENSE 

Regenerative medicine provision plans accepted by Ministry of Health, Labor and Welfare

  • License for cell culturation

  • License of MSC with old cerebral infarction

  • Acceptance Certificate for PRP Osteoarthritis

  • License of MSC with teeth

  • License of MSC transplantation into joints

  • License of MSC with MACCE

  • License of MSC with hair loss

  • License of MSC in cosmetics

  • License of MSC and MSC-derived exosomes with immure frailty

  • License of MSC and MSC-derived exosomes with Type 2 diabetes

  • Acceptance letter for type 1 diabetes administration

  • female hormone imbalance Intravenous administration receipt

  • Receipt for subcutaneous administration to the face

  • License of Male Erectile Dysfunction

  • License of Acceptance for Neurodegenerative Disorders

  • License of Acceptance for Elderly Skin Changes

  • NK cell administration receipt

We storage in a special tank containing liquid nitrogen at minus 196 ° C. Long-term storage is possible.
Immediately after collection of stem cells
stem cell 1
MACS
Stem cell check
Cell testing equipment

FACILITY 

Facility of Omotesando cell culture laboratory

Cell Conditioning Facility (CPC) Cell culture is carried out under strict sanitary controls as follows. Inside the clean bench, ISO class 5 (class 100) clean air is supplied, keeping the interior clean. In order to grow and manage cells, cell conditioning facilities (CPCs) must meet very high standards to reduce the number of particles and create a sterile room free of bacteria. In addition, to ensure a high level of safety, we conduct virus tests when cells are received. Furthermore, we have established a cell culture operation management system that incorporates a strict quality control system that includes barcode management (traceability system) and history management of all processes to prevent sample mistakes.

Sự khác biệt về mỡ tùy thuộc vào vị trí thu thập »

关于我院的干细胞培养技术和培养基 »

*Actual footage of stem cell proliferation

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BEGGINNER'S GUIDE 

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