HELENE CLINIEC
TOKYO Helene AO ​​Building Clinic LONDON EDINBUGH DUBAI ABU DHABI
TOKYO Helene AO ​​Building Clinic LONDON EDINBUGH DUBAI ABU DHABI

List of diseases

Diseases for which administration of mesenchymal stem cells is effective

Arteriosclerosis Diabetes immunosuppression knee pain periodontal disease hair regeneration skin regeneration type 1 diabetes Female hormone imbalance (menopause) neurodegenerative diseases male erectile dysfunction Senile skin changes
Professor of Clinical Microbiology, University of Cambridge
Professor Ravindra Gupta

Professor Gupta leads the Gupta Laboratory which has extensively studied HIV drug resistance at both the molecular and population levels. He has contributed to the assessment of the global scale of drug resistance. The group's work has also extended to the study of HIV reservoirs in cells, especially macrophages. This understanding is relevant both to the anatomical compartment in which HIV viral replication occurs in macrophages and to the design of strategies to treat HIV. The Gupta Lab is located in the United Kingdom and Durban, South Africa, and collaborates with the African Institute of Health Research.

In March 2019, Gupta led a team for an investigation of HIV-positive patients with Hodgkin lymphoma who have progressed after "unrelated" stem cell transplantation. It was reported that this London Patient's patients' HIV remission was demonstrated.

Career

  • Professor of Clinical Microbiology, Institute of Immunology and Infectious Disease Treatment, University of Cambridge
  • Members of the African Health Research Institute in Durban, South Africa
  • Selected as one of Time Magazine's ``100 Most Influential People of 2020''
  • Selected as "The World's Most Influential Microbiologist" in 2022
For the full version of the video, go to the next slide »
Cutting-edge technology and innovative approaches to MSC culture at Helene Clinic

Ravindra Gupta, Distinguished Professor of Microbiology and Infectious Diseases at the University of Cambridge, shared his insights into the potential of stem cells at the Helen Clinic.

In a special interview, Mr. Gupta spoke about the challenges and opportunities associated with culturing large quantities of MSCs (mesenchymal stem cells), emphasizing the importance of maintaining purity and remaining vigilant throughout the process. He praised Hellene Clinic's efforts to achieve the culture of 2.25 billion MSCs, particularly the multilayer culture flasks, specialized "Helene Growth Medium" and strict quality to ensure pure MSCs reach patients. Emphasis was placed on a combination of management measures.

Addressing concerns about tumor formation, Gupta reassured that due to stem cells' strict self-regulatory mechanisms, the risk of stem cells developing into cancer cells is minimal and may even reduce the risk of cancer development. I let it happen.

Regarding the use of exosomes, Mr. Gupta expressed enthusiasm about their therapeutic potential. He emphasized the importance of exosomes in signal transduction and reducing inflammation, and noted the compatibility of exosomes across different patients with minimal immune detection. Mr. Gupta also praised Helene Clinic's rigorous purification and testing methods for exosomes, which ensure quality and efficacy. He discussed the possibility of combining mesenchymal stem cell therapy with exosomes and envisioned a synergistic effect that could enhance therapeutic outcomes.

Overall, the esteemed professor at the University of Cambridge praised the Helene Clinic's cutting-edge technology and innovative approach, confirming that it is at the forefront of stem cell therapy research and application.

Professor of Clinical Microbiology, University of Cambridge
Professor Ravindra Gupta

Professor Gupta leads the Gupta Laboratory which has extensively studied HIV drug resistance at both the molecular and population levels. He has contributed to the assessment of the global scale of drug resistance. The group's work has also extended to the study of HIV reservoirs in cells, especially macrophages. This understanding is relevant both to the anatomical compartment in which HIV viral replication occurs in macrophages and to the design of strategies to treat HIV. The Gupta Lab is located in the United Kingdom and Durban, South Africa, and collaborates with the African Institute of Health Research.

In March 2019, Gupta led a team for an investigation of HIV-positive patients with Hodgkin lymphoma who have progressed after "unrelated" stem cell transplantation. It was reported that this London Patient's patients' HIV remission was demonstrated.

Career

  • Professor of Clinical Microbiology, Institute of Immunology and Infectious Disease Treatment, University of Cambridge
  • Members of the African Health Research Institute in Durban, South Africa
  • Selected as one of Time Magazine's ``100 Most Influential People of 2020''
  • Selected as "The World's Most Influential Microbiologist" in 2022
*For the full version of the video, go to the next slide
Helene Clinic's cutting-edge technology and innovative approaches on MSC cultivation

Cambridge University's renowned professor in microbiology and infectious diseases, Ravindra Gupta, shared his insights on the potential of Helene's stem cells.

In a special interview, Gupta discussed the challenges and opportunities associated with culturing large quantities of MSCs (Mesenchymal Stem Cells), emphasizing the importance of maintaining purity and vigilance throughout the process. He commended Helene Clinic's efforts to achieve a cultivation of 22.5 billion MSCs, particularly highlighting the combination of multi-layered culture flasks, specialized "Helene growth medium," and stringent quality control measures to ensure the delivery of pure MSCs to patients.

Addressing concerns about tumor formation, Gupta infantred that due to the strict self-regulatory mechanisms of stem cells, the risk of them developing into cancer cells is minimal, and they may even reduce the risk of cancer occurrence.

Regarding the use of exosomes, Gupta expressed enthusiasm for their therapeutic potential. He emphasized the importance of exosomes in signal transduction and reducing inflammation, noting their compatibility across different patients due to minimal immune detection. Gupta also praised Helene Clinic's rigorous purification and testing methods for exosomes, ensuring quality and efficacy. He discussed the possibility of combining mesenchymal stem cell therapy with exosomes and envisioned a synergistic effect that could enhance treatment outcomes.

Overall, Cambridge University's esteemed professor recommended Helene Clinic for its cutting-edge technology and innovative approaches, confirming its position at the forefront of stem cell therapy research and application.

TOPICS

  • menopause

Menopausal Symptoms and Hormone Replacement Therapy (HRT) | A Complete Guide to Benefits, Side Effects, and Costs

Some women may be enduring the painful menopausal symptoms that appear one after another, such as hot flashes, sweating, irritability, and insomnia, all on their own. For women suffering from painful menopausal symptoms, there is an effective treatment option called hormone replacement therapy (HRT). However, when you hear the word "hormones," some people may imagine that it can have scary side effects. In this article, we will explain the correct information about hormone replacement therapy, including its benefits, side effects, and costs. What is hormone replacement therapy (HRT)? Hormone replacement therapy (HRT) is a treatment that uses medication to supplement small amounts of the female hormone (estrogen), which decreases rapidly during menopause. By supplementing female hormones, hot flashes can be reduced.
2025/10/31
  • menopause
  • heart
  • muscle

Causes of menopausal weight gain and how to eliminate it | Measures you can take with exercise, diet, and supplements

When you hear about menopausal weight gain, many people may think it's a problem for women. However, it's not uncommon for men in their 40s and older to have concerns like, "I'm careful about my diet and exercise, but I just can't seem to lose the fat around my stomach..." The cause of menopausal weight gain may not be overeating or lack of exercise, but rather a "decrease in testosterone" due to male menopause (LOH syndrome). In this article, we'll explain the causes of menopausal weight gain that are unique to men, and what measures can be taken with exercise, diet, and supplements. Two reasons why menopausal weight gain is more likely to occur The reason people gain weight after turning 40 is not a lack of willpower, but a decline in male hormones (testosterone).
2025/10/23
  • menopause

[At what age does menopause begin?] Early symptoms and a checklist women should know

"I haven't been feeling well lately." "I've become easily irritated over small things. Could it be because I'm getting older?" Many women are probably confused by the changes in their mind and body that they've experienced since turning 40. These unexplained discomforts may be a sign that menopause is beginning. Menopause is a natural change in life that all women experience. With a proper understanding, you can cope with the changes well and live more comfortably. What is menopause? At what age does it start? Menopause is when the activity of the ovaries gradually disappears and menstruation stops permanently. When it has been confirmed that menopause has stopped for one year since the last menstruation, menopause can be diagnosed retroactively, going back one year.
2025/10/15

Multilingual(Interpreter resident)

Japanese, English, Chinese, Cantonese, Shanghainese, Minnan, French, Mongolian, Vietnamese, Tagalog, Malay, Korean, Indonesian

STEMCELL 

Stem cell therapy

Stem cells are cells with the ability of re-activating weakened cells and increasing

number of cells that are important to our body function but decreasing every day.

What is a stem cell?  

The mechanism of mesenchymal stem cell treatment  

Indications  

The risks of stem cell therapy  

Research papers  

academic activities 

LICENSE 

Regenerative medicine provision plans accepted by Ministry of Health, Labor and Welfare

  • Images of European Association for Quality Research ESQR 2025

    European Quality Research Association
    ESQR 2025

  • European Society for Quality Research ESQR images

    European Quality Research Association
    ESQR 2024

  • ABRM certified clinic images

    American Society for Regenerative Medicine
    Japan branch

  • GCR certificate image

    Global Clinic Rating
    international certification

  • ISO9001 certificate

    Certification ISO 9001

     
  • License for cell culturation

  • License of MSC with old cerebral infarction

  • Acceptance Certificate for PRP Osteoarthritis

  • License of MSC with teeth

  • License of MSC transplantation into joints

  • License of MSC with MACCE

  • License of MSC with hair loss

  • License of MSC in cosmetics

  • License of MSC and MSC-derived exosomes with immure frailty

  • License of MSC and MSC-derived exosomes with Type 2 diabetes

  • Acceptance letter for type 1 diabetes administration

  • female hormone imbalance Intravenous administration receipt

  • Receipt for subcutaneous administration to the face

  • License of Male Erectile Dysfunction

  • License of Acceptance for Neurodegenerative Disorders

  • License of Acceptance for Elderly Skin Changes

  • NK cell administration receipt

We storage in a special tank containing liquid nitrogen at minus 196 ° C. Long-term storage is possible.
Immediately after collection of stem cells
stem cell 1
MACS
Stem cell check
Cell testing equipment

FACILITY 

Facility of Omotesando cell culture laboratory

Cell Conditioning Facility (CPC) Cell culture is carried out under strict sanitary controls as follows. Inside the clean bench, ISO class 5 (class 100) clean air is supplied, keeping the interior clean. In order to grow and manage cells, cell conditioning facilities (CPCs) must meet very high standards to reduce the number of particles and create a sterile room free of bacteria. In addition, to ensure a high level of safety, we conduct virus tests when cells are received. Furthermore, we have established a cell culture operation management system that incorporates a strict quality control system that includes barcode management (traceability system) and history management of all processes to prevent sample mistakes.

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关于我院的干细胞培养技术和培养基 »

*Actual footage of stem cell proliferation

FAQQ/A 

FAQ

BEGGINNER'S GUIDE 

Beginner's Guide

SUPPORT 

Support